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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Zap2it Best/Worst | 2006 | TV Gal's Best in Show (#7) | Winner | |
| Zap2it Best/Worst | 2005 | TV Gal's Best in Show (#9) | Winner | |
| Zap2it Best/Worst | 2004 | TV Gal's Best in Show (#8) | Winner | |
| Young Artist Award | 2003 | Best Performance by a Young Actress (Ten or Under) Guest-Starring in a Television Comedy or Drama Series | Nominee | Alexandra Lee |
| Writers Guild Award | 2003 | Best Writing in an Episodic Comedy Series for Television | Nominee | Bill Lawrence |
| Wand Award | 2002 | Best Guest Star | Nominee | Brendan Fraser |
| Wand Award | 2002 | Comedy You Can't Live Without | Nominee | |
| Wand Award | 2002 | Breakout Star, Male Breakout Star, Male Breakout Star, Male Breakout Star, Male Breakout Star, Male | Nominee | Zach Braff |
| Wand Award | 2002 | Best New Show Best New Show Best New Show Best New Show | Nominee | |
| Wand Award | 2002 | Favorite Funnyguy | Nominee | Zach Braff |
| Voice Award | 2005 | Television | Winner | |
| Tubey Award | 2007 | Best HoYay! Moment (#2) | Voted | Guy Love song |
| Tubey Award | 2006 | Best Credit Sequence (#3) | Voted | |
| Tubey Award | 2006 | Best Relationship (#2) | Voted | J.D. & Turk |
| Tubey Award | 2006 | Best Comedy (#3) | Voted | |
| Tubey Award | 2006 | Most Overlooked Show (#3) | Voted | |
| Tubey Award | 2005 | Best Comedy (#2) | Voted | |
| Tubey Award | 2005 | Most Overlooked Show (#3) | Voted | |
| Tubey Award | 2004 | Best Returning Show (#3) | Voted | |
| Tubey Award | 2004 | Best Sitcom (#2) | Voted | |
| Tubey Award | 2004 | Most Overlooked Show (#2) | Voted | |
| Tubey Award | 2004 | Favourite Actor (#3) | Voted | John C. McGinley |
| Tubey Award | 2004 | Best Guest Star (#1) | Voted | Brendan Fraser |
| TelevisionWeek's Critics Poll | 2006.02 | Best Television (#13) | Winner | |
| TelevisionWeek's Critics Poll | 2005.01 | Best Television (#17) | Winner | |
| TelevisionWeek's Critics Poll | 2004.01 | Best Television (#12) | Winner | |
| Television Critics Association Award | 2006 | Outstanding Achievement in a Comedy Series | Nominee | |
| Television Critics Association Award | 2002 | Outstanding Achievement in a Comedy Series | Nominee | |
| Television Critics Association Award | 2002 | Outstanding Individual Achievement in a Comedy Series | Nominee | John C. McGinley |
| TeeVee Award | 2005 | Best Half-Hour Actor | Winner | Donald Faison |
| TeeVee Award | 2003 | Best Half-Hour Actress | Winner | Sarah Chalke |
| TeeVee Award | 2003 | Best Half-Hour Show | Winner | |
| TeeVee Award | 2002 | Best Half-Hour Show | Winner | |
| TeeVee Award | 2002 | Best Half-Hour Actor | Winner | John C. McGinley |
| Teen Choice Award | 2007 | Choice TV Sidekick | Nominee | Donald Faison |
| Teen Choice Award | 2006 | Choice TV Sidekick | Nominee | Donald Faison |
| Teen Choice Award | 2006 | Choice TV Actor - Comedy | Nominee | Zach Braff |
| Teen Choice Award | 2005 | Choice TV Actor in a Comedy Series | Nominee | Zach Braff |
| Teen Choice Award | 2005 | Choice TV Comedy Series | Nominee | |
| Teen Choice Award | 2005 | Choice TV Sidekick | Nominee | Donald Faison |
| Teen Choice Award | 2004 | Choice TV Actor in a Comedy Series | Nominee | Zach Braff |
| Teen Choice Award | 2004 | Choice TV Sidekick | Nominee | Donald Faison |
| Teen Choice Award | 2004 | Choice TV Comedy Series | Nominee | |
| Teen Choice Award | 2003 | Choice TV Actor in a Comedy Series | Nominee | Zach Braff |
| Teen Choice Award | 2003 | Choice TV Actress in a Comedy Series | Nominee | Sarah Chalke |
| Teen Choice Award | 2003 | Choice TV Comedy Series | Nominee | |
| Teen Choice Award | 2002 | Choice TV Actor in a Comedy Series | Nominee | Zach Braff |
| Teen Choice Award | 2002 | Choice TV Comedy Series | Nominee | |
| Spirit Award | 2003 | in Media | Winner | |
| RATTY Award | 2007 | Best Comedy Series | Nominee |
