Plot Synopsis

WATSON takes place six months after the death of the titular character's friend and partner Sherlock Holmes at the hands of Moriarty. Dr. John Watson resumes his medical career in Pittsburgh, PA, as the head of a clinic dedicated to treating rare disorders. Watson's old life isn't done with him, though -- Moriarty and Watson are set to write their own chapter. Watson is a medical show with a strong investigative spine, featuring a modern version of one of history's greatest detectives as he turns his attention from solving crimes to solving medical mysteries. WATSON premiered on Sunday, January 26, 2025 on CBS at approximately 10pm ET/7pm PT, immediately follows the postgame for the AFC Championship Game between the Buffalo Bills and Kansas City Chiefs. WATSON moves to its regular timeslot -- Sundays at 9pm ET/PT on CBS -- beginning February 16, the week after the Super Bowl.
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On Sunday, May 11, 2025 at 9pm ET/PT, CBS premiered "Your Life's Work (Part 2)," the Season 1 finale of WATSON. Watson and the team are faced with an impossible choice when two lives hang in the balance, but they only have one vial of antidote available. Meanwhile, Shinwell races to help the team, and Watson goes head to head with Moriarty. Randall Park returns as James Moriarty. Tika Sumpter guest stars as Laila, a pediatric oncologist.

WATSON has been renewed for a second season.