Two and a Half Men
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| Award (↑) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Emmy Award | 2005 | Outstanding Supporting Actress in a Comedy Series | Nominee | Conchata Ferrell |
| Emmy Award | 2004 | Outstanding Art Direction for a Multi-Camera Series | Nominee | |
| Emmy Award | 2004 | Outstanding Cinematography for a Multi-Camera Series | Nominee | Steven V. Silver |
| Emmy Award | 2004 | Outstanding Main Title Theme Music | Nominee | Chuck Lorre; Lee Aronsohn; Grant Geissman |
| GLAAD Media Award | 2005 | Outstanding Individual Television Episode | Nominee | |
| Golden Globe Award | 2006 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Charlie Sheen |
| Golden Globe Award | 2005 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Charlie Sheen |
| Golden Laurel Award | 2006 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Internet TV Award | 2006 | Favorite Actor in a Primetime Comedy Series | Nominee | Charlie Sheen |
| Internet TV Award | 2004 | Favorite Actor in a Primetime Comedy Series | Nominee | Charlie Sheen |
| Kids Choice Award | 2007 | Favorite TV Actor | Nominee | Charlie Sheen |
| MediaVillage TV Fan Award | 2006 | Outstanding Comedy Series | Nominee | |
| MediaVillage TV Fan Award | 2006 | Outstanding Actor in a Comedy Series | Nominee | Jon Cryer |
| MediaVillage TV Fan Award | 2006 | Outstanding Actor in a Comedy Series | Nominee | Charlie Sheen |
| Mr. Skin's Anatomy Award | 2005 | Best Network TV Scene | Winner | Kristin Dattilo |
| Parents Television Council Award | 2005 | Worst Family Shows on Primetime Network TV (#7) | Winner | |
| Parents Television Council Award | 2004 | Worst Family Shows on Primetime Network TV (#4) | Winner | |
| People's Choice Award | 2008 | Favorite Male TV Star | Nominee | Charlie Sheen |
| People's Choice Award | 2008 | Favorite Television Comedy Series | Winner | |
| People's Choice Award | 2007 | Favorite Male TV Star | Nominee | Charlie Sheen |
| People's Choice Award | 2007 | Favorite Television Comedy Series | Winner | |
| People's Choice Award | 2006 | Favorite Male Television Performer | Nominee | Charlie Sheen |
| People's Choice Award | 2004 | Favorite New Television Comedy Series | Winner | |
| RATTY Award | 2005 | Best Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| RATTY Award | 2004 | Best Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| RATTY Award | 2004 | Best Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| RATTY Award | 2004 | Best New Series | Nominee | |
| Screen Actors Guild Award | 2005 | Outstanding Performance by an Actor in a Television Comedy Series | Nominee | Charlie Sheen |
| SHINE Award | 2004 | Scene Stealer | Nominee | |
| Teen Choice Award | 2008 | Choice TV Show - Comedy | Nominee | |
| Teen Choice Award | 2008 | Choice TV Actor - Comedy | Nominee | Charlie Sheen |
| Teen Choice Award | 2007 | Choice TV Actor - Comedy | Winner | Charlie Sheen |
| TV Guide Award (televised) | 2004 | Favorite Comedy Star | Nominee | Charlie Sheen |
| TV Times Readers' Choice | 2005 | Best Actor in a Comedy (#3) | Voted | Charlie Sheen |
| TV Times Readers' Choice | 2004 | Best Actor in a Comedy (#4) | Voted | Charlie Sheen |
| TV Times Readers' Choice | 2004 | Best Comedy Series (#5) | Voted | |
| Variety Top 10 | 2007 | 10 Funniest Scenes (#9) | Winner | |
| Viewers Voice Award | 2006 | Favorite Half-Hour Show | Winner | |
| Viewers Voice Award | 2006 | Favorite Actor in a Comedy Series | Winner | Charlie Sheen |
| Viewers Voice Award | 2006 | Favorite Supporting Actor in a Comedy Series | Winner | Jon Cryer |
| Viewers Voice Award | 2005 | Favorite Half-Hour Show | Nominee | |
| Viewers Voice Award | 2005 | Favorite Supporting Actress in a Comedy | Nominee | Holland Taylor |
| Wave Awards | 2008 | Favorite Clipped Comedy Artist | Nominee | Charlie Sheen |
| Young Artist Award | 2008 | Best Performance by a Leading Young Actor in a Television Comedy or Drama Series | Nominee | Angus T. Jones |
| Young Artist Award | 2006 | Best Performance by a Supporting Young Actor in a Television Comedy Series | Winner | Angus T. Jones |
| Young Artist Award | 2004 | Best Performance by a Young Actor (Ten or Under) in a Television Comedy or Drama Series | Winner | Angus T. Jones |
| Young Artist Award | 2004 | Best Family Television Comedy or Drama Series | Nominee |
