Plot Synopsis

Executive produced and hosted by longtime acquaintances and Bronx natives Desus Nice and The Kid Mero, DESUS & MERO is a weekly, late-night, half-hour series, where the quick-witted duo brings a distinct voice to late night, delivering smart and comedic commentary on any and all topics, that keeps audiences buzzing. Fellow Bronx native, Rep. Alexandria Ocasio-Cortez (D-NY), is their first guest. After a 2.5-month break, DESUS & MERO returned with new episodes on Monday, October 14, 2019 at 11pm ET/PT. The mid-season premiere, "It's a Boy," featured rapper DaBaby.

DESUS & MERO returned for its second season on Monday, February 3, 2020 at 11pm ET/PT on Showtime. In the season opener, "PJ Boys," Desus and Mero welcome special guest David Letterman.

Season 3 of DESUS & MERO debuted on Sunday, January 31, 2021 on Showtime, continuing to air weekly on Sunday and Thursday nights at 11pm ET/PT from New York City. In the season opener, "Right Off the Rip," Desus Nice and The Kid Mero welcome guest Stacey Abrams, as they sound off on pop culture, politics, sports and more, now coming to you from their own homes.
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The fourth season of DESUS & MERO premiered on Thursday, March 10, 2022 at 11pm ET/PT on Showtime, with Denzel Washington joining Desus Nice and The Kid Mero in studio for the season opener. Returning to its original weekly schedule with new episodes dropping every Thursday night, the late night series features the duo giving their take on the day's hot topics and chatting with guests at the intersection of pop culture, sports, music, politics and more. Upcoming guests this season include Mark Wahlberg and Tom Holland, Pusha T and Damson Idris.