Malcolm in the Middle
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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Young Star Award | 2000 | Best Performance by a Young Actor in a Comedy Television Series | Winner | Frankie Muniz |
| Young Star Award | 2000 | Best Young Ensemble Cast in a Television Series | Winner | |
| Young Artist Award | 2005 | Best Performance by a Recurring Young Actor in a Television Comedy or Drama Series | Winner | Cameron Monaghan |
| Young Artist Award | 2004 | Most Popular Mom & Dad in a Television Series | Nominee | Jane Kaczmarek |
| Young Artist Award | 2004 | Most Popular Mom & Dad in a Television Series | Nominee | Bryan Cranston |
| Young Artist Award | 2003 | Best Performance by a Leading Young Actor in a Television Comedy or Drama Series | Nominee | Frankie Muniz |
| Young Artist Award | 2003 | Best Performance by a Supporting Young Actor in a Television Comedy or Drama Series | Nominee | Justin Berfield |
| Young Artist Award | 2003 | Best Performance by a Young Actor Guest-Starring in a Television Comedy Series | Nominee | Miles Marsico |
| Young Artist Award | 2003 | Best Performance by a Young Actress Guest-Starring in a Television Comedy Series | Nominee | Lauren Storm |
| Young Artist Award | 2003 | Best Performance by a Young Ensemble in a Television Comedy or Drama Series | Winner | |
| Young Artist Award | 2002 | Best Performance by a Leading Young Actor in a Television Comedy Series | Winner | Frankie Muniz |
| Young Artist Award | 2002 | Best Performance by a Supporting Young Actor in a Television Comedy Series | Nominee | Craig Lamar Traylor |
| Young Artist Award | 2002 | Best Performance by a Young Actor Guest-Starring in a Television Comedy Series | Nominee | Bobby Brewer |
| Young Artist Award | 2002 | Best Performance by a Young Actress Guest-Starring in a Television Comedy Series | Winner | Brooke Ann Smith |
| Young Artist Award | 2002 | Best Performance by a Young Actor (Ten or Under) in a Television Comedy or Drama Series | Nominee | Erik Per Sullivan |
| Young Artist Award | 2002 | Best Performance by a Young Ensemble in a Television Comedy or Drama Series | Nominee | |
| Young Artist Award | 2002 | Best Family Television Comedy Series | Winner | |
| Young Artist Award | 2001 | Best Performance by a Leading Young Actor in a Television Comedy Series | Winner | Frankie Muniz |
| Young Artist Award | 2001 | Best Performance by a Supporting Young Actor in a Television Comedy Series | Winner | Craig Lamar Traylor |
| Young Artist Award | 2001 | Best Performance by a Young Performer Guest-Starring in a Television Comedy Series | Nominee | Ashley Turner |
| Young Artist Award | 2001 | Best Performance by a Young Actor (Ten or Under) in a Television Comedy or Drama Series | Nominee | Erik Per Sullivan |
| Young Artist Award | 2001 | Best Performance by a Young Ensemble in a Television Comedy or Drama Series | Nominee | |
| Writers Guild Award | 2007 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| Writers Guild Award | 2006 | Best Writing in an Episodic Comedy Series for Television | Nominee | Rob Ulin |
| Writers Guild Award | 2005 | Best Writing in an Episodic Comedy Series for Television | Winner | Neil Thompson |
| Writers Guild Award | 2004 | Best Writing in an Episodic Comedy Series for Television | Nominee | Gary Murphy, Neil Thompson |
| Writers Guild Award | 2004 | Best Writing in an Episodic Comedy Series for Television | Nominee | Dan Kopelman |
| Writers Guild Award | 2002 | Best Writing in an Episodic Comedy Series for Television | Nominee | Alex Reid |
| Writers Guild Award | 2002 | Best Writing in an Episodic Comedy Series for Television | Nominee | Gary Murphy, Neil Thompson |
| Wand Award | 2002 | Favorite Funnygirl | Nominee | Jane Kaczmarek |
| Wand Award | 2002 | Comedy You Can't Live Without | Nominee | |
| Viewers Voice Award | 2002 | Favorite Actress in a Comedy | Nominee | Jane Kaczmarek |
| Viewers Voice Award | 2002 | Favorite Young Actor in a Primetime Series | Nominee | Frankie Muniz |
| Viewers Voice Award | 2002 | Favorite Half-Hour Series | Nominee | |
| Viewers Voice Award | 2001 | Favorite Half-Hour Series | Nominee | |
| Viewers Voice Award | 2001 | Favorite Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Viewers Voice Award | 2001 | Favorite Young Actor | Winner | Frankie Muniz |
| Viewers for Quality Television Award | 2000 | Best Actress in a Quality Comedy Series | Nominee | Jane Kaczmarek |
| TV Times Readers' Choice | 2005 | Best Actress in a Comedy (#5) | Voted | Jane Kaczmarek |
| TV Guide's All Time Greatest/Worst Lists | 2002 | 50 Greatest TV Theme Songs (2000) | Winner | |
| TV Guide Award (televised) | 2004 | Favorite Comedy Star | Nominee | Jane Kaczmarek |
| TV Guide Award (televised) | 2001 | Favorite Breakout Star | Nominee | Frankie Muniz |
| Time Magazine's Best/Worst List | 2000 | Top Ten Best Television Shows (#2) | Winner | |
| TelevisionWeek's Best of 25 Years | 2007 | Broadcast's Best of Past 25 Years | Winner | |
| Television Critics Association Award | 2001 | Outstanding Comedy Series | Winner | |
| Television Critics Association Award | 2001 | Outstanding Individual Achievement in a Comedy Series | Nominee | Bryan Cranston |
| Television Critics Association Award | 2001 | Outstanding Individual Achievement in a Comedy Series | Winner | Jane Kaczmarek |
| Television Critics Association Award | 2000 | Outstanding Comedy Series | Winner | |
| Television Critics Association Award | 2000 | Outstanding New Program of the Year | Nominee | |
| Television Critics Association Award | 2000 | Outstanding Individual Achievement in a Comedy Series | Winner | Jane Kaczmarek |
